Searchable abstracts of presentations at key conferences in endocrinology

ea0063s5.1 | Microbiota as new treatment for diabetes and metabolic disease | ECE2019

Human gut microbiome: hopes, threats and promises

VIDAL Hubert

The gut microbiota is now the subject of considerable investigation and our knowledge of its composition and understanding of functions are rapidly growing.Gut microbiota has profound impact on host physiology and it is now well-established that dysbiosis is associated with altered glycemic control and type 2 diabetes development. Targeting microbiota appears therefore as a promising strategy for the treatment of diabetic patients. Using probiotics in order to modulate blood g...

ea0063gp230 | Adrenal and Neuroendocrine - Clinical (1) | ECE2019

Low-dose pollutant mixture triggers metabolic disturbances in ovariectomized mice and comparison with the effects of 17β-estradiol (E2) treatment

Julien Benoit , Vega Nathalie , Pinteur Claudie , Vidal Hubert , Naville Danielle , Le Magueresse-Battistoni Brigitte

Introduction: Environmental pollutants especially those endowed with endocrine disrupting activities have been shown to contribute to metabolic related diseases suggesting that hormonal deficit conditions as observed in post-menopausal women may constitute aggravating conditions. To explore this hypothesis, we used the model developed in the laboratory which consists in a chronically exposure of mice to low-dosed chemicals in mixture incorporated in a high-fat-high-sucrose die...